High Throughput Screening (HTS)
High-throughput screening (HTS) is a method for scientific experimentation that allows for the rapid screening of large numbers of chemical, genetic, or pharmacological compounds for a specific biological activity. HTS is used in various fields, including drug discovery, materials science, and biology.
The HTS Workflow
HTS is performed using a variety of techniques, but the general workflow is as follows:
Compound Preparation: The compounds to be screened are prepared in a liquid format, typically using a robotic system.
Assay: The compounds are added to a biological assay measuring the desired physical activity.
Detection: The results of the assay are then detected using a variety of methods, such as fluorescence, luminescence, or mass spectrometry.
Data Analysis: The data from the assay is then analyzed to identify the compounds with the desired biological activity.
Applications of HTS
HTS can screen millions of compounds daily, making it a powerful tool for drug discovery and other research applications. Here are some examples of how HTS is performed in Jivakana cell technologies:
Drug Discovery: HTS can screen large libraries of chemical compounds for potential drug candidates. This can help to identify new drugs that are new and have fewer side effects than existing ones.
Materials Science: HTS can screen new materials for desired properties, such as strength, durability, or conductivity. This can help to develop new materials for a variety of applications.
Biology: HTS can be used to screen genes or proteins for their role in biological processes. This can help understand the disease’s molecular basis and develop new therapies.
HTS is a powerful tool that is used in a variety of fields to accelerate scientific research.